In particular scenarios like breast cancer, CSCs identified as BCSCs (Breast cancer stem cells) exist in specific development states, the first one being in a mesenchymal state expressing CD24-/CD44+ markers on their cell surface and the second being in an epithelial cell-like state expressing an enzyme known as Aldehyde dehydrogenase (ALDH) (80). Here, LDHA is linked to breast carcinoma.