CXCL8 and respiratory syncytial virus bronchiolitis: Consistent with our findings, increased levels of the chemokine CXCL8 (also known as IL8) in plasma, bronchial secretions, and nasopharyngeal aspirates have been associated with the severity of RSV bronchiolitis in infants, as evidenced by the need for oxygen or mechanical ventilation, Silverman scores, and hypoxemia (19–22).