Induced by anti-inflammatory stimuli such as IL-4, IL-10, IL-13, glucocorticoids and immune complexes, macrophages secrete high levels of IL-10 and increase the expression of mannose receptors and galactose receptors (21), thus acting as an anti-inflammatory agent to promote wound healing and tissue repair, as well as to promote proliferation, metastasis, angiogenesis, and endocytosis of tumor cells (Figure 2). The gene discussed is IL4; the disease is neoplasm.