Analysis of the over- or under-representation of single nucleotide polymorphisms (SNPs) in the genes of all 57 human P450 as well as their three redox partners revealed that in 26 out of 57 P450 as well as in two out of the three redox partners SNPs with a very high over-representation (odds ratio of >5) were found in PD patients compared to healthy controls. The gene discussed is CYP2B6; the disease is Parkinson disease.