SIRT1 and cancer: The combination of chemotherapy with other SIRT1 inhibitors, such as suramins, JGB1741, tenovins, salermide, sirtinol, and other class III HDAC inhibitors, might enhance the efficacy of cancer treatments by regulating autophagy and inducing associated cell death (Lin and Fang, 2013; Heltweg et al., 2006; Lara et al., 2009; Kalle et al., 2010; Lain et al., 2008; Asaka et al., 2015).