In the patients with “overlapping FLD”, the proportion of elevated ALT (ALT>33 U/L in men and ALT>25 in women) is 36.1%, advanced liver fibrosis is defined as NFS >0.675 is 1.5%, cirrhosis is 0.01%, and hepatocellular carcinoma (HCC) is 0.03%. This evidence concerns the gene GPT and Cirrhosis.