Previous studies investigating chemokines associated with lymphocyte rich TMEs in melanoma observed altered expression of CCL2, CCL3, CCL4, CCL21, CXCL10, CXCL11, and CXCL13, all of which are ligands expressed by the tumor within the RDI network (Source Data)22,23. The gene discussed is CXCL10; the disease is melanoma.