TPD52 isoform 3, a member of the TPD52 (tumor protein D52) family, appears to be involved in trafficking via the exo‐ and endocytic pathways.[10] In addition, evidence has shown that phosphorylation‐dependent regulation of TPD52 in turn regulates endolysosomal trafficking in secretory cell types.[11] In cancers, accumulating evidence indicates an oncogenic role for TPD52. Here, TPD52 is linked to cancer.