SF1 and Hypoglycemia: Contemporary studies, using combinative in situ immunocytochemistry/laser-catapult-microdissection/single-cell multiplex qPCR methodology together with a validated in vivo experimental model for IIH (Paranjape & Briski, 2005), showed that VMNdm growth hormone-releasing hormone (Ghrh) neurons contain hypoglycemia-sensitive SF-1 mRNA, and that Ghrh neurotransmission is crucial for hypoglycemic counterregulatory hormone secretion patterns (Sapkota et al., 2023).