miR-140-5p was the most positively changing miRNA in the following seven pathways: adipogenesis, clear cell renal cell carcinoma pathways (CCRCCP), epidermal growth factor/epidermal growth factor receptor (EGF/EGFR), endochondral ossification, endochondral ossification with skeletal dysplasia (EOSD), gastrin signalling pathway, and vascular endothelial growth factor-A/vascular endothelial growth factor receptor 2 signalling pathway (VEGFA-VEGFR2). The gene discussed is EGFR; the disease is skeletal dysplasia.