LASSO regression analysis showed that 11 disulfidptosis‐related genes (including FLNA, GLUT, GYS1, LRPPRC, MYH9, NCKAP1, NDUFS1, NUBPL, RPN1, SLC3A2 and SLC7A11) were associated with sepsis (Figure 6C,D). This evidence concerns the gene RPN1 and Sepsis.