We found that only level ALKBH7 reduced in tumor tissues (Tumor) than that in the adjacent tissues (Normal), although the other ALKBH family genes of elevated during the tumor development (Figure 1C), while the outhouse datasets of HNSC (E_MTAB _8588, GSE42743, and GSE75538) also illustrated the reduction of ALKBH7 expression in HNSC tumor tissues (Figure 1D), indicating that ALKBH7 might be involved in HNSC tumor growth and development. This evidence concerns the gene ALKBH7 and neoplasm.