Ferroptosis-related genes (FRGs) that are abnormally expressed in ccRCC cells relative to normal cells include CARS1, CHAC1, CD44, STEAP3, AKR1C1, DPP4, SLC7A11, SLC1A5, and NCOA4 (98–101). The gene discussed is CD44; the disease is nonpapillary renal cell carcinoma.