ACLY and metastatic malignant neoplasm in the lymph nodes: Multivariate Cox regression was used to construct clinical prediction model, and results showed that ACLY expression (HR 1.88, 95% CI 1.04-3.40; P=0.04), Vascular invasion (HR 2.37, 95%CI 1.30-4.32; P=0.00) and regional lymph node metastasis (HR 3.36, 95% CI: 1.86-6.09; P=0.00) were independent risk factors (Figure 2D).