CD4 and fibrosis: Genes such as PECAM1, VCAM1, ICAM2, FN1, CD44, CD2, CD8A, and IL7R were expressed in endothelial and immune cells (CD8+ and CD4+ T-cells, natural killer (NK) cells and mononuclear phagocytes) (22), suggesting that these cells may be the main actors producing the LGALS1 interactome and that the expression of these genes is altered in the setting of fibrosis.