The precise pathophysiology of ROP is not completely elucidated; however the widely accepted theory is the two‐phase theory7, 8: Phase I begins with the initiation of infant breathing, where the oxygen saturation of the developing retina in the premature baby is relatively higher than in the intrauterine state, leading to attenuated production of vascular endothelial growth factor (VEGF) in the retina, suspending vascularization. Here, VEGFA is linked to retinopathy of prematurity.