Radiomics have been widely studied in the classification of benign and malignant lung tumors (16), differentiation of different histological types of lung cancer (17), prediction of lung cancer prognosis (18), evaluation of treatment effects (19), prediction of genotypes in pulmonary adenocarcinoma (20), prediction of PD-L1 expression and tumor mutation burden (21) and differentiation of immune pneumonitis from radiation pneumonitis (22). The gene discussed is CD274; the disease is lung carcinoma.