Additionally, recent sequencing studies have identified genetic mutations linked to CD on chromosome 7, including BRAF (MAPK pathway, 7q34), WEE2 (7q34), lysine methyltransferase 2E {KMT2E} (chromatin remodeling, 7q22), histone deacetylase 9 {HDAC9} (chromatin remodeling, 7p21), and dynein axonemal heavy chain 11 {DNAH11} (cell function, 7p15) [9,10]. Here, HDAC9 is linked to Cowden disease.