ALK and lung carcinoma: Moreover, novel therapeutic molecules designed to induce pyroptosis have also been reported, such as B-Raf proto-oncogene, serine/threonine kinase (BRAF) (Erkes et al. 2020) and Mitogen-activated protein kinase kinase (MEK) inhibitors for treating melanoma and small-molecule inhibitors for lung cancers targeting Kirsten rat sarcoma viral oncogene homolog (KRAS), Epidermal growth factor receptor (EGFR), or Anaplastic lymphoma kinase (ALK) (Lu et al. 2018).