Moreover, novel therapeutic molecules designed to induce pyroptosis have also been reported, such as B-Raf proto-oncogene, serine/threonine kinase (BRAF) (Erkes et al. 2020) and Mitogen-activated protein kinase kinase (MEK) inhibitors for treating melanoma and small-molecule inhibitors for lung cancers targeting Kirsten rat sarcoma viral oncogene homolog (KRAS), Epidermal growth factor receptor (EGFR), or Anaplastic lymphoma kinase (ALK) (Lu et al. 2018). This evidence concerns the gene ALK and melanoma.