Some isoforms of the PLA2, Dis, and Ctm-like myotoxin families have been described to show modulatory effect in insulin resistance models (Marinovic et al., 2018; Moore et al., 2015; Nogueira et al., 2005; Toyama et al., 2005), as Glib, these peptides can sensitize the β-pancreatic cells to insulin (Finneran and Landon, 2018). The gene discussed is INS; the disease is Insulin resistance.