The CDC73 gene is also suspected to be implicated in MEN1 phenocopy, since the report of a patient with a clinical diagnosis of MEN1, based on the combined occurrence of normocalcemic PHPT at age 70 years, acromegaly diagnosed at age 22 years, and a pancreatic NET at age 70 years, harboring a heterozygous c.1138C>T p.(Leu380Phe) CDC73 germline variant suspected to be pathogenic (68). Here, CDC73 is linked to pancreatic neuroendocrine tumor.