In GSEA results, FAM166B in PCOS was mainly enriched in signaling pathways such as Insulin secretion, Fructose and mannose metabolism, Regulation of lipolysis in adipocytes, Inflammatory mediator regulation of TRP channels, Carbohydrate digestion and absorption, Steroid biosynthesis and Platelet activation. The gene discussed is CIMIP2B; the disease is polycystic ovary syndrome.