IFNG and neoplasm: The contemplation of GRASLND as a therapeutic target aims to potentially enhance immunogenicity by increasing HLA-I antigen processing and presenting machinery (HLA-I-APM) in response to IFNγ, but also increase the multifaceted anti-tumor effects of IFNγ signaling, such as inducing apoptosis and inhibiting angiogenesis (Jorgovanovic et al., 2020).