It has also been reported that sEH inhibitors attenuate TGF-β signaling in a model of pulmonary fibrosis,53 and dual inhibition of cyclooxygenase and sEH protects against liver fibrosis54 and the TGF-β-driven development of epithelial to mesenchymal transformation in the lung.55 The gene discussed is EPHX2; the disease is pulmonary fibrosis.