These genes were CD74 and SUMO3. The presence of one variant with an odds ratio (OR) of SUMO3 (OR: 0.775; 95 % CI: 0.619–0.970; p = 0.044) potentially correlated with a reduced risk of diabetic kidney disease (Supplementary Table 3), while the CD74 gene (OR: 1.474; 95 % CI: 1.128–1.926; p = 0.004) was linked to an elevated risk (Supplementary Table 4). This evidence concerns the gene CD74 and diabetic kidney disease.