GPX4 and acute myeloid leukemia: Numerous substances, including eprenetapopt (APR-246), aldehyde dehydrogenase 3 family member A2 (ALDH3A2), poly(lactic acid)-glycolic acid-encapsulated glycyrrhetinic acids (GCMNPs), glutathione-bioimprinted nanoparticles targeting of N6-methyladenosine FTO demethylase (GNPIPP12MA), gold nanorods (GnR) functionalized with chitosan and a 12-mer peptide 12 (GnRA-CSP12) and GCFN, have been found to induce ferroptosis in AML cells by disrupting the balance between GSH and ROS and inhibiting GPX4 synthesis (51,66–69).