RARRES2 and myocardial infarction: Thus, our findings of a robust positive association between circulating RARRES2 and MI are consistent with the previous cohort studies.13,39 RARRES2, also known as chemerin, is mainly expressed in adipose tissue and has been implicated in the regulation of adipogenesis, immune response regulation, glucose metabolism, and inflammation.40 The results of our MR analysis suggested a causal role of elevated levels of RARRES2 in the risk of MI.