86). More importantly, the study reported that activated platelets via CLEC2 produced extracellular vesicles that activated neutrophils and macrophages via CLEC5A and TLR2 and contributed to the formation of neutrophil extracellular traps (NETs). NET level in the plasma was reported to inversely correlate with platelet count and positively correlate with P-selectin expression during days 7–13 of disease in acute dengue patients (Ref. 87). Here, CLEC1B is linked to dengue disease.