High expression of FZD7, TP63, and genes related to and GSH metabolism was also found in the ovarian cancer and residual human ovarian cancer samples after chemotherapy.208 The platinum-tolerant cell population may exhibit characteristics of cancer stem cells, and platinum-resistance may be related to the FZD7-β-catenin-Tp63-GPX4 pathway. The gene discussed is GPX4; the disease is cancer.