In addition, ARNTL2 knockdown decreases N-cadherin expression and increases the expression of β-catenin and E-cadherin in lung adenocarcinoma cells, while the opposite effects are observed in ARNTL2-overexpressed cells,118 suggesting that ARNTL2 overexpression may promote EMT by inhibiting ferroptosis. This evidence concerns the gene BMAL2 and lung adenocarcinoma.