CIRBP and cardiac arrest: Results of RNA-Seq showed that the expression of cold-inducible RNA-binding protein (Cirbp) decreased in the elderly donor heart due to low temperature, leading to severe ferroptosis in recipient hearts after transplantation.512 Overexpression of Cirbp in the elderly donor heart and supplementation of cardiac arrest fluid with Cirbp agonists reversed the effects of hypothermia.512