SLC7A11 and Parkinson disease: Consumption of GSH can promote ferroptosis by decreasing SLC7A11 and GPX4 expression in dopaminergic neurons of PD patients.558 For example, hypermethylation of cg06690548 on chromosome 4 in PD patients is associated with downregulation of SLC7A11, which may be a possible biological target for PD.600