SLC7A11 and ischemic stroke: HUC-MSCs-derived exosomes enhance the viability of hypoxia/reperfusion (H/R)-exposed cells and inhibit ferroptosis.783 Mechanically, HUC-MSCs-derived exosomes inhibit ferroptosis by delivering circBBS2, which sponges miR-494 and enhances SLC7A11 levels, thereby inhibiting ferroptosis and alleviating ischemic stroke.783 Stem-cell derived exosome therapy targeting ferroptosis is proved to be a novel strategy against cerebral I/R injury.