FTO level is upregulated in PD model, while FTO silencing alleviates cell ferroptosis.597 In addition, bioinformatics analysis shows that Nrf2 is the target of FTO, and FTO impairs Nrf2 mRNA stability through an m6A dependent pathway, revealing the potential function of FTO in PD neurological diseases.597. Here, NFE2L2 is linked to Parkinson disease.