Mechanically, ADSC-Exos are effectively delivered to the brain through the intranasal administration and is enriched with miR-760-3p to downregulate the expression of CHAC1 and inhibit ferroptosis.782 Exosomes secreted by human umbilical cord mesenchymal stem cells (HUC-MSCs) are considered to be an effective treatment for ischemic stroke. Here, CHAC1 is linked to ischemic stroke.