CDH2 and lung cancer: lncRNA-LINC00641 is significantly downregulated in lung cancer tissue than that in the neighboring normal lung tissue, and its downregulation is associated with poor prognosis in lung adenocarcinoma.113 Knockdown of LINC00641 increases N-cadherin levels by upregulating Human antigen R (HuR) protein, ultimately promoting EMT.114 Notably, LINC00641 knockdown in lung cancer cells increases ferroptosis sensitivity by promoting arachidonic acid metabolism.114 This is inconsistent with findings that inhibiting ferroptosis promotes EMT in other tumors.