To investigate the role of HIF‐2α in RCC, the expression of HIF‐2α was measured in various RCC cells, including A498 (human renal cell carcinoma cell), ACHN (human renal adenocarcinoma cell), and 786‐O (human renal adenocarcinoma cell). The gene discussed is EPAS1; the disease is papillary renal cell carcinoma.