VHL and renal carcinoma: Studies have shown that long noncoding RNA‐SARCC could inhibit the proliferation of VHL mutant renal cancer cells and promote the proliferation of VHL normal renal cancer cells by regulating the androgen receptor /HIF‐2α/C‐MYC axis under the hypoxic microenvironment.[14] Furthermore, studies have indicated that HIF‐2α is critical for the function of regulatory T cells, and targeting HIF‐2α shows potential for effectively inhibiting tumor growth.[15]