During ICD, cancer cells produce various signaling molecules, including CRT exposed on the cell surface, HMGB1, ATP molecules, and heat shock proteins (HSP70, HSP90).[22] To verify whether APm/Ce6/HIF+US inhibited the proliferation of renal cancer cells via ICD, the expression of CRT on the cell surface in 786‐O cells was measured by immunofluorescence staining. This evidence concerns the gene ANPEP and cancer.