As demonstrated by Penova-Vaselinovic et al. in 2015 (7), lower levels of inflammatory mediators such as IL-1β, IL-10, IL-12p70, and IL-6 were found in the crevicular fluid of pregnant patients with periodontal disease who received SRP (experimental group) compared to those who did not (control group). This evidence concerns the gene IL6 and periodontal disorder.