Moreover, PA-induced hepatocytes secrete miR-107-enriched EVs, which activate HSCs by suppressing dickkopf-1 (DDK1) and Th9 cell differentiation by mediating Forkhead box protein P1 (Foxp1), exacerbating MASH-related liver fibrosis [53]. The gene discussed is FOXP1; the disease is Hepatic fibrosis.