For instance, lnc-DDX60-1 is located downstream of the DDX60 gene, which encodes an RNA binding protein involved in antiviral responses [44], and RP11-202G18.1 is located upstream of LPAR1, which encodes a G-protein coupled receptor involved in pulmonary fibrosis and response to tissue damage and infectious agents [45]. Here, LPAR1 is linked to pulmonary fibrosis.