MAP4K4 and metabolic dysfunction-associated steatotic liver disease: However, given the complexity of MASLD pathophysiology, it is important to expand the analysis to additional cell types, including neutrophils, lymphocytes, dendritic cells, and liver sinusoidal endothelial cells, which are also known to contribute to MASLD development (90, 91, 92) and express high levels of both the GCKIII kinases and their key interaction partners (i.e., PDCD10, MAP4K4, and HSD17B11) https://www.livercellatlas.org/index.php, http://www.liverproteome.org/.