Moreover, Stk25 knockout mice and mice treated with Stk25- or Mst3-targeting antisense oligonucleotides are protected against the deleterious effects of MASH-inducing diet, with livers displaying lowered steatosis, inflammatory infiltration, fibrosis, and cellular damage highlighted by ballooning and apoptosis (18, 21, 22, 23, 24). Here, STK25 is linked to steatosis.