The fold changes in mRNA expression of Bad (p = 0.003 and p = 0.009) and Bak (p = 0.005 and p = 0.008) were significantly decreased while was increased for Bax (p = 0.005and p = 0.03) in BE and in EAC tissues compared to the normal esophageal tissues. Here, BAD is linked to Barrett esophagus.