FN1 and colorectal carcinoma: Another study investigating the ability of CRC-derived Fn subspecies to colonize murine models also profiled the genomic differences between previously sequenced Fn genomes (Figure 2).27 Consistent with the previous report, Fn subspecies genomes clustered tightly into distinct phylogenomic groups, with strain-level variations being relatively minor in comparison to the large distinctions observed between subspecies.