Indeed, aberrant soluble N‐ethylmaleimide‐sensitive factor attachment protein receptor protein–protein (SNARE)‐mediated secretion, facilitated by SNAP25, STX1, and VAMP, is linked with multiple neurological diseases with cognitive impairment as a core feature, including encephalopathy, schizophrenia, and dementia.45 This evidence concerns the gene STX1A and dementia.