Conversely, stimulating mTOR with MHY1485 reduced GLUT1 levels (Fig. 6J and Supplementary Fig. S11A), These intricate interplays underscore a reciprocal relationship between glycolysis and mTORC1 in ALDH-active endometrial cancer progression (Supplementary Fig. S12). The gene discussed is MTOR; the disease is endometrial cancer.