For instance, there was an increased frequency of sEPSCs onto YH-HET SST neurons, suggestive of a compensatory increase in excitatory input to counteract their reduced intrinsic excitability and increase their AP firing, as has been observed previously in hypoexcitable SST neurons in another epilepsy model (Halabisky et al., 2010). The gene discussed is SST; the disease is epilepsy.