Downregulation of several endosomal TLRs (TLR3, 7 and 21 after CSW-1 ILTV infection and TLR7 after ΔgG ILTV) in LMH cells, was consistent with the results of a previous study that reported a reduction in mRNA levels for TLR3 and TLR7, and an inconclusive level of expression of TLR21 in LMH cells inoculated with ILTV [71]. The gene discussed is TLR3; the disease is infection.