PET/CT imaging studies of AR42J tumor-bearing 394-NOD SCID mice at 1 h after injection of [68Ga]Ga-DOTA-CCK-66 (1.1 MBq, n = 5) confirmed an increased tumor uptake in all five mice (SUVmax = 2.02 ± 0.77%), while overall non-target tissue uptake was low, with only one exception being the kidneys (Fig. 3, Supplemental Fig. 2). This evidence concerns the gene CCK and neoplasm.