Legumain activity is associated with numerous inflammatory diseases, including pancreatitis, atherosclerosis, neuroinflammation, and cancer (Edgington‐Mitchell et al., 2016; Lei et al., 2021; Lunde et al., 2017; Z. H. Wang et al., 2017; Z. H. Wang et al., 2021; Wu et al., 2020; Xia et al., 2020). The gene discussed is LGMN; the disease is pancreatitis.