Univariate analysis screened out some clinical factors significantly associated with KPLA, including younger males, the presence of diabetes mellitus and fatty liver, absence of liver malignancy, liver cirrhosis and splenomegaly, the presence of cryptogenic liver abscess, higher RBC count and Hb and CRP levels, and lower ALP, DBIL, and IBIL levels (all p < 0.05). The gene discussed is GSTM1; the disease is diabetes mellitus.