FANCA and Fanconi anemia: In humans, previous studies have already shown that patients harboring biallelic pathogenic variants in genes such as FANCA, FANCM, FANCD1, FANCU, as well as those with monoallelic pathogenic variants in FANCA, FANCD1, FANCL, presented with gonadal dysfunction and infertility with or without other phenotypic features of Fanconi Anemia (74).