ELAVL1 and nasopharyngeal carcinoma: To investigate the role played by HMGB3 in ELAVL1-mediated glycolysis in nasopharyngeal carcinoma cells, we overexpressed HMGB3 in cells with knockdown of ELAVL1, and found that overexpression of HMGB3 significantly alleviated the reduced glucose consumption, decreased lactate production, and decreased G6PD activity caused by sh-ELAVL1 (Fig. 5A-C).