DLEU2 and osteoporosis: To identify new potential therapeutic targets for bone diseases caused by increased resorption activity, such as osteoporosis, the expression of ncRNAs located at chr13q14.2, specifically DLEU1/DLEU2/miR-15a/miR-16-1 (Supplementary Fig. 1), was evaluated during the 9 days of osteoclastogenic differentiation from six human blood donors.