For example, we found that GID4 interacts with the Rb transcriptional corepressor 1 (RBL1), the MAU2 sister chromatid cohesion factor and the CCCTC-binding factor (CTCF), and the transcription factor ZNF106, which has been implicated in growth-related metabolism associated with early multiple organ failure in acute pancreatitis (Ciosk et al, 2000; Grasberger et al, 2005; Henley & Dick, 2012; Liu & Dekker, 2022; van den Berg et al, 2022). The gene discussed is CTCF; the disease is acute pancreatitis.