Specifically, we analyzed retinal samples from Pde6βRd10 and RhoP23H/WT (in short, rd10 and P23H) mouse models of autosomal recessive and autosomal dominant retinitis pigmentosa (RP), respectively; and samples from the Rpe65−/− mouse model of LCA2. The gene discussed is RPE65; the disease is retinitis pigmentosa 1.