The aim of this study was to compare Gleason 7 (3+4) and Gleason 7 (4+3) adenocarcinomas with different prognostic criteria: impairment of the surgical margin of resection, impairment of the vesical margin, impairment of the urethral margin and impairment of seminal vesicles through an immunohistochemical analysis with anti-PSA, anti-Ki 67 and anti-AMARC antibodies. Here, KLK3 is linked to adenocarcinoma.