We analyzed cilia defects in three CNS regions implicated in scoliosis appearance: the spinal cord central canal (since scoliosis develops in the spine), the forebrain choroid plexus (fChP) whose cilia defects have been associated with scoliosis in katnb1-/- fish (Meyer-Miner et al., 2022) and the subcommissural organ (SCO), which secretes SCO-spondin whose absence leads to scoliosis (Rose et al., 2020; Troutwine et al., 2020). Here, KATNB1 is linked to scoliosis.