Since rpgrip1l is ubiquitously expressed in zebrafish (Mahuzier et al., 2012), scoliosis could have different tissue origins, including a neurological origin as shown for the ptk7 and ktnb1 scoliotic fish (Meyer-Miner et al., 2022; Van Gennip et al., 2018). The gene discussed is PTK7; the disease is scoliosis.